25–26 Feb 2025
IFIN-HH/ ELI-NP Training Center
Europe/Bucharest timezone

Tumor segmentation from scattering images obtained with a Talbot-Lau interferometer using Convolutional Neural Networks

26 Feb 2025, 10:15
15m
IFIN-HH/ ELI-NP Training Center

IFIN-HH/ ELI-NP Training Center

Speaker

Ionut Cristian Ciobanu (XIL)

Description

Detecting breast tumors using imaging techniques remains a critical challenge in medical diagnostics, with limitations in contrast and resolution affecting early detection. Traditional mammography methods struggle to differentiate between healthy and tumorous tissue, particularly in cases with low-density differences. This study investigates the potential of combining ultrahigh-sensitivity Talbot-Lau interferometry with Convolutional Neural Networks (CNNs) to enhance breast tumor segmentation from scattering images. The research aims to improve tumor detection accuracy and efficiency by leveraging phase contrast imaging. The experimental setup utilized an ultrahigh-sensitivity Talbot-Lau interferometer operated with a conventional X-ray tube to generate scattering images, which were processed using a Fourier Transform-based algorithm. Five CNN architectures - U-Net, ResNet50, DeepLabV3, PSPNet, and SegNet -were trained and tested. Performance was evaluated based on accuracy, precision, specificity, recall, and F1-score. U-Net demonstrated the most stable performance with an accuracy of 86.34% and an F1-score of 90.2%, making it the most reliable model for tumor segmentation in scattering images. The combination of Talbot-Lau interferometry with CNNs presents a promising approach for breast tumor detection. U-Net emerged as the most stable model, suggesting its potential application in medical diagnostics. Future work should focus on optimizing CNN architectures and expanding the dataset to improve the segmentation of small tumor-like masses.

Presentation materials